Two for the price of one! Not only does the atmospherically-charged super-villain, The Weather Wizard, make his first appearance in this book, but more importantly Kid Flash (who later appears as one of the Teen Titans characters) also makes his bow.
Teen Titans are hot due to (you guessed it) movie hype. The team's first appearance in Brave and the Bold #54 appears at #98 on our Hot 100 list.
Add to that the complication that this is a relatively scarce Silver Age book, especially in grades above VG, and you will conclude that Flash #110 is probably a good investment bet.
Other Flash books on the Hot 100:
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