2017 MARKET UPDATE:
It's confirmed! After all the speculation, Michael Keaton will be The Vulture in the wasn't-Marvel-anymore-but-now-will-be reboot of Spider-Man: Homecoming.
As if that wasn't enough, it's the third-ever appearance of Spidey, and a true Silver Age key issue. The fuss about this book is justified. I doubt whether it will suffer much price-wise after the movie has come and gone. Scarce in higher grades.
Of all the bad guys on the Spider-Man villains list, the Vulture has perhaps the most potential from an investment standpoint.
Sorry for the amateurish quality of the following YouTube clip, but it demonstrates the excitement around the Vulture's potential appearance in a future Spider-Man movie project:
There are a bunch of question marks since that trailer was released. An actor's IMDB profile included mention he had signed for the project and was due to play the Vulture. Then it was removed again, and the entire Spider-Man reboot with Andrew Garfield seems to have been shelved.
That doesn't mean the Vulture won't feature at some point, maybe as part of a Sinister Six project. The Sinister Six first appeared in Amazing Spider-Man Annual #1, so it might be worth grabbing a copy of that book too.
We didn't include the annual in our Hot 100 list, because since Garfield's Spidey movie series has been cancelled, prices have come down on that book as speculators dumped their copies.
Other Amazing Spider-Man books on the Hot 100:
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